

Where is the lesion?
Left iliac bone
What are the radiological characteristics/findings?
Large lytic lesion with wide zone of transition, cortical destruction, and large soft tissue component.
No specific matrix.
What is the differential diagnosis of an aggressive iliac bone lesion?
* Metastasis
* Plasmacytoma: solitary plasma cell tumor expansile lytic lesion with bone destruction and soft tissue component. Usually shows low signal intensity on T2 with variable post contrast enhancement.
* Chondrosarcoma: malignant cartilage tumor destructive lytic lesion with intralesional rings and arcs calcification (chondroid matrix). High signal intensity on T2.
What is the most likely diagnosis?
Plasmacytoma