Musculoskeletal #3 – Long case

Axial CT abdomen bone window

Axial CT abdomen soft tissue window

Where is the lesion?

Left iliac bone

What are the radiological characteristics/findings?

Large lytic lesion with wide zone of transition, cortical destruction, and large soft tissue component.
No specific matrix.

What is the differential diagnosis of an aggressive iliac bone lesion?

* Metastasis
* Plasmacytoma: solitary plasma cell tumor expansile lytic lesion with bone destruction and soft tissue component. Usually shows low signal intensity on T2 with variable post contrast enhancement. 
* Chondrosarcoma: malignant cartilage tumor destructive lytic lesion with intralesional rings and arcs calcification (chondroid matrix). High signal intensity on T2. 

What is the most likely diagnosis?

Plasmacytoma

Musculoskeletal #2 – Flashcard

13-year-old girl with knee pain for 2 months.

What do you see?

Click here to see the answer

Periphyseal (both knees) hyperintensity on sagittal fat suppressed T2 Weighted image (a) and Proton Density Weighted image (b) and hypointensity on sagittal T1Weighted image (c) (arrows).

FOPE: Focal periphyseal edema
– Mostly around the knees
– Both genders can be affected during skeletal maturation
– Painful manifestation of physiologic physeal fusion